If your platform isn't supported by SiDock@home or you don't like precompiled binaries, you can use Anonymous platform.

For Gentoo it's quite simple:

# eselect repository enable guru
# USE=boinc emerge cmdock

If you're not using Gentoo but still want to compile CmDock yourself follow these steps...

1. Download and unpack CmDock 0.1.2 source code (GitLab link)
   
2. Get meson somewhere and run in the sources directory:
   
   

   meson setup --prefix /opt/cmdock-0.1.2 build
   meson compile
   meson install
   

   
   
3. Go to project's directory:
   
   

   /var/lib/boinc/projects/www.sidock.si_sidock/

   
   
4. Download XML files there
   
5. Download and unpack boinc wrapper for your platform or compile it. Place it into project's directory as two files named cmdock-wrapper_0.1.2 and cmdock-boinc-zip_wrapper_0.1.2
   
6. Create empty file docking_out.sd
   
7. Make sure /opt/cmdock-0.1.2/build/cmdock and all listed below files exist:
   
   

   /var/lib/boinc/projects/www.sidock.si_sidock
   ├── app_info.xml
   ├── cmdock-boinc_job_0.1.2.xml
   ├── cmdock-boinc-zip_job_0.1.2.xml
   ├── cmdock-boinc-zip_wrapper_0.1.2
   ├── cmdock-wrapper_0.1.2
   └── docking_out.sd
   

   
   
8. Restart BOINC, make sure it detected anonymous platform and tasks don't fail
   

Note: I haven't detected any perfomance increase with -march=native optimizations. Maybe there are some with LTO.

Will this approach in the case of AArch64 (64-bit ARM) prevent the code of cmdock to look for libstdc++.so.6 in the wrong (32-bit) directory?

yes

Note: if you use CmDock v0.1.4 (the latest at the moment), step 6 should read:
6. Create empty file docking_out

UPD: As Gentoo files are updated, you need to replace @PREFIX@ in wrapper jobs with an actual path (e.g. /opt/cmdock-0.1.4):

$ sed "s|@PREFIX@|/opt/cmdock-0.1.4|g" -i cmdock-boinc-zcp_job_0.1.4.xml

Replace "meson setup --prefix /opt/cmdock-0.1.2 build" with "meson setup --prefix /opt/cmdock-0.2.0 build"
"meson compile" with "meson compile -C build"
and "meson install" with " sudo meson install -C build"

Then add following in /etc/profile
export CMDOCK_ROOT=/opt/cmdock-0.2.0
export PATH=$CMDOCK_ROOT/bin:$PATH
export LD_LIBRARY_PATH=$CMDOCK_ROOT/lib:$LD_LIBRARY_PATH
export PERL5LIB=$CMDOCK_ROOT/lib:$PERL5LIB

I used

meson setup  --prefix /opt/cmdock-0.2.0 build --buildtype release --optimization=3 -Dcpp_args=' -pipe -march=native  -mtune=native -flto '  -Dc_args=' -pipe -march=native  -mtune=native -flto '

 meson compile -C build -j 8

sudo meson install -C build

app_info.xml

<app_info>
<app>
        <name>cmdock-s</name>
        <user_friendly_name>CurieMarieDock 0.2.0 short tasks</user_friendly_name>
</app>
<app>
        <name>cmdock-l</name>
        <user_friendly_name>CurieMarieDock 0.2.0 long tasks</user_friendly_name>
</app>
<file_info>
        <name>cmdock-s_wrapper_0.2.0</name>
        <sticky/>
        <executable/>
</file_info>
<file_info>
        <name>cmdock-l_wrapper_0.2.0</name>
        <sticky/>
        <executable/>
</file_info>
<file_info>
        <name>cmdock</name>
        <sticky/>
        <executable/>
</file_info>
<file_info>
        <name>cmdock-l_job_0.2.0.xml</name>
        <sticky/>
</file_info>
<file_info>
        <name>cmdock-s_job_0.2.0.xml</name>
        <sticky/>
</file_info>
<file_info>
        <name>docking_out</name>
        <sticky/>
</file_info>

<app_version>
        <app_name>cmdock-s</app_name>
        <version_num>100</version_num>
        <file_ref>
                <file_name>cmdock-s_wrapper_0.2.0</file_name>
                <main_program/>
        </file_ref>
        <file_ref>
                <file_name>cmdock</file_name>
                <open_name>cmdock</open_name>
                <copy_file/>
        </file_ref>
        <file_ref>
                <file_name>cmdock-s_job_0.2.0.xml</file_name>
                <open_name>job.xml</open_name>
                <copy_file/>
        </file_ref>
        <file_ref>
                <file_name>docking_out</file_name>
                <open_name>docking_out</open_name>
                <copy_file/>
        </file_ref>
</app_version>
<app_version>
        <app_name>cmdock-l</app_name>
        <version_num>100</version_num>
        <file_ref>
                <file_name>cmdock-l_wrapper_0.2.0</file_name>
                <main_program/>
        </file_ref>
        <file_ref>
                <file_name>cmdock</file_name>
                <open_name>cmdock</open_name>
                <copy_file/>
        </file_ref>
        <file_ref>
                <file_name>cmdock-l_job_0.2.0.xml</file_name>
                <open_name>job.xml</open_name>
                <copy_file/>
        </file_ref>
        <file_ref>
                <file_name>docking_out</file_name>
                <open_name>docking_out</open_name>
                <copy_file/>
        </file_ref>
</app_version>
</app_info>

cmdock-s_job_0.2.0.xml

<job_desc>
        <task>
                <application>cmdock</application>
                <stdout_filename>docking_log</stdout_filename>
                <command_line>-c -j 1 -b 1  -r target.prm -p "/opt/cmdock-0.2.0/data/scripts/dock.prm" -f htvs.ptc -i ligands.sdf -o docking_out</command_line>
                <checkpoint_filename>docking_out.chk</checkpoint_filename>
                <fraction_done_filename>docking_out.progress</fraction_done_filename>
                <setenv>CMDOCK_ROOT=/opt/cmdock-0.2.0/</setenv>
                <setenv>LD_LIBRARY_PATH=/opt/cmdock-0.2.0/lib:$LD_LIBRARY_PATH</setenv>
                <setenv>PERL5LIB=/opt/cmdock-0.2.0/lib:$PERL5LIB</setenv>
        </task>
        <unzip_input>
                <zipfilename>ligands.zip</zipfilename>
        </unzip_input>
</job_desc>

cmdock-l_job_0.2.0.xml

<job_desc>
    <task>
        <application>cmdock</application>
        <stdout_filename>docking_log</stdout_filename>
        <command_line>-c -j 1 -b 1  -r target.prm -p "/opt/cmdock-0.2.0/data/scripts/dock.prm" -f htvs.ptc -i ligands.sdf -o docking_out</command_line>
        <checkpoint_filename>docking_out.chk</checkpoint_filename>
        <fraction_done_filename>docking_out.progress</fraction_done_filename>
        <setenv>CMDOCK_ROOT=/opt/cmdock-0.2.0/</setenv>
        <setenv>LD_LIBRARY_PATH=/opt/cmdock-0.2.0/lib:$LD_LIBRARY_PATH</setenv>
        <setenv>PERL5LIB=/opt/cmdock-0.2.0/lib:$PERL5LIB</setenv>
    </task>
    <unzip_input>
        <zipfilename>ligands.zip</zipfilename>
    </unzip_input>
</job_desc>

Then i created symlink with

ln -s /opt/cmdock-0.2.0/bin/cmdock cmdock

and created empty file with

touch docking_out

Also downloaded boinc wrapper from https://boinc.berkeley.edu/dl/wrapper_26014_x86_64-pc-linux-gnu.zip
extracted, copied and renamed to cmdock-s_wrapper_0.2.0 and cmdock-l_wrapper_0.2.0

hello

---