What is SiDock@home?

Sidock@home is an international volunteer computing project aimed at drug discovery. The first mission of the project is discovery of possible drugs against the SARS-CoV-2 virus. It started as an extension of the project COVID.SI to engage the BOINC community into the drug discovery.

 COVID.SI is a citizen science project to fight against SARS-CoV-2 by distributed computing.

You can help with your computer. With the help of BOINC, you will download a subset of compounds on your computer, examine the compounds in the context of the studied target and send the results to a server where they are collected for later analysis.

For account creation please use a Crunch_4Science invitation code. It is not needed when registering by BOINC Manager.

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User of the Day

User profile Profile Thyler Durden@P3D
Hello calculator for science, I have been with the DC at Seti @ home since the year 2000 and counted on the team oc-card. After the legendary 999Wu...


SiDock@home becomes a general drug discovery project
Hello everyone!

We are happy to announce that SiDock@home will continue as a general drug discovery project, not limited to coronavirus only! This means that the project will continue for a long time. We aim to develop and incorporate novel methods of drug design and perform drug discovery for different diseases.

Nevertheless, the first mission on fighting the coronavirus continues! There are many results to process and more targets to explore within what started from COVID.SI project.

With best wishes,
Natalia and the team.
27 Feb 2021, 14:06:38 UTC · Discuss

Fourth target (corona_RdRp_v1)
We are glad to announce the fourth target, corona_RdRp_v1. This molecule is frequently used in research studies as a potential target to inhibit viral replication. Specifically, it is SARS-CoV-2 RNA-dependent RNA polymerase (RdRp in short), an enzyme which coronavirus SARS-CoV-2 uses for the replication of its genome and the transcription of its genes.
8 Feb 2021, 8:17:30 UTC · Discuss

Release CMDock v 0.1.1
Official release of CurieDock (CMDock v 0.1.1) for windows, linux and arm (raspberry pi):

5 Feb 2021, 19:10:12 UTC · Discuss

Third target (corona_PLpro_v2)
Hello everyone!

We are glad to announce work on the third target: PLpro_v2, the same protein with another catalytic active site.
We resume task generation with a new validator. It was implemented to automate result check which caused some delays before.

Thank you all for supporting the project!
29 Jan 2021, 10:21:40 UTC · Discuss

Temporary task shortage
Hello everyone! There is a temporary task shortage due to finishing the 2nd target, moving to the 3rd one and improving the docking protocol. Thank you for your patience!
21 Jan 2021, 15:30:02 UTC · Discuss

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