BOINC client 7.16.20 solves the certificate problem for Windows
Dear all,

If you are running BOINC on a Windows computer, please update to a new version (7.16.20) of the BOINC client. The previous version stopped working recently because of an expired SSL file that prevented it from communicating with several BOINC projects, with the BOINC server, and with Science United. You can download the new version here:

With best wishes,
Team of SiDock@home
20 Oct 2021, 8:03:32 UTC · Discuss

Certificates and project communicating
Dear folks!

If BOINC on your computer experiencing a problem during project communicating, try to replace file ca-bundle.crt in programs directory of BOINC (C:\Program Files\BOINC\ca-bundle.crt, for example) by this file: and restart whole BOINC processes or reboot computer.

Another threads on forum:
Peer certificate cannot be authenticated with given CA certificates
Wus not uploading
Transient Error
Communication deferred
100% block still crunching

Thank you for participation!
4 Oct 2021, 18:55:28 UTC · Discuss

4000 users with credit
Dear SiDockers,

new breakthrough of the project, we will wellcome 4000th user with the credit, very soon.

;-) Crtomir
21 Sep 2021, 15:17:51 UTC · Discuss

SiDock@home September Sailing
Dear participants!

Just now, your computers are hitting three protein targets at once. Due to the low runtimes and (mainly) the friendly contributions of participants and their teams, the data is being processed fast, and we express our gratitude to all of you.
We announce a new competition between teams, SiDock@home September Sailing. Top winners will get the badges:
1st place:

2nd place:

3rd place:

Heme B, the well-known ligand in the complex of Hemoglobin, helps to carry oxygen in our bloodstream. As we know today, it has emerged from just two mutations that occurred in genome of one of predecessors of modern vertebrates more than 400 million years ago [1,2].

[2] Pillai, A.S., Chandler, S.A., Liu, Y. et al. Origin of complexity in haemoglobin evolution. Nature 581, 480–485 (2020).
12 Sep 2021, 8:19:15 UTC · Discuss

Targets six, seven, eight
Dear participants,

we have prepared three new targets for you! They all base on 3CLpro protein, a prime target for antiviral drug discovery because of its central involvement in virus replication. Another reason to put them high on the list is that we have a good possibility to test interesting results in a lab. The targets 6, 7 and 8 are X-ray identified allosteric sites on 3Clpro. We will make a limited number of workunits to ensure everything works fine, and then launch full-scale screening on the new targets. We will temporarily pause processing of Target 5 in favour of the new ones.

With best wishes,
Team SiDock@home
28 Aug 2021, 16:18:49 UTC · Discuss

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What is SiDock@home?

Sidock@home is an international volunteer computing project aimed at drug discovery. The first mission of the project is discovery of possible drugs against the SARS-CoV-2 virus. It started as an extension of the project  COVID.SI to engage the BOINC community into the drug discovery.

You can help with your computer. With the help of BOINC, you will download a subset of compounds on your computer, examine the compounds in the context of the studied target and send the results to a server where they are collected for later analysis.

For account creation please use a Crunch_4Science invitation code. It is not needed when registering by BOINC Manager.

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J'aime apprendre, découvrir et être moins bourricot jour après jour :)

Donations to SiDock@home

We are going to use donation money for biological evaluation of results.

This project is accepting donations in cryptocurrency:
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  • Bitcoin wallet (BTC): 3GaQD2EBsEAgvdPdpkMGJP3JT5zM3uKNn3
  • Ethereum wallet (ETH): 0xd726c8a048c0532e4793D88895d3cE1A637517c8
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